optrcdmaeAT (1.0.0)

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Optimal Row-Column Designs for Two-Colour cDNA Microarray Experiments.


Computes A-, MV-, D- and E-optimal or near-optimal row-column designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all pairwise treatment contrasts. The algorithms used in this package are based on the array exchange and treatment exchange algorithms adopted from Debusho, Gemechu and Haines (2016, unpublished) algorithms after adjusting for the row-column designs setup. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.

Maintainer: Dibaba Bayisa Gemechu
Author(s): Legesse Kassa Debusho, Dibaba Bayisa Gemechu, and Linda Haines

License: GPL-2

Uses: igraph, MASS, Matrix

Released about 3 years ago.



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